V8 to Slant Six swap: Sacrilege to must, but what would need to be done to have it happen?

The easiest is a K frame change and the proper engine mounts,you would be good to go. Lots of slant frames for the A's.Heck you could buy a complete donor car for the same as just buying a K frame.Sell off the extra parts and make money.
You are not the only one thinking of doing this.I want to do the same with a B body.Hope to find a 1970 slant K for a B. Also thinking of changing my 68 Valiant to a slant from a 273 (maybe)..

If you do find a V8 stick car you won't be able to use the fly wheel or the bell housing as they are different.