Choosing pistons

Evan Dutch said
By larger heads. I do mean more open. I will be running an intercooler as I would most likely be driving this car more street than track. I would prefer the compression lower so that the car is more "streetable" (if that makes any sense). From what I've seen in the replies to this post I will most likely go with the dish pistons.

Just be aware that open chambers can run LESS psi and are more prone to detonation.

Evan Dutch said
After thought, I would like to keep the boost below 12. Car will be tubbed and springs relocated. I would like to run a 46rh trans.

As a rule of thumb for boost. Every 14.7 psi is about double horsepower (I say about cause things like air temp, tune, etc etc can decrease that). Because that's atmospheric pressure. A 300 horse 408 small block will make 545 horse at 12 psi. And it's preeeety darn hard to make a 408 stroker with only 300 horse. So keep that in mind.