Sure, I've used the 800 Edelbrock carb on a bunch of Mopar stroker engines. They make really good street carbs. The idle circuit in the Carter/Edelbrock design is much better than a Holley idle circuit so the engine will idle much smoother even with a big cam. The 800 flows well enough to get you up to the 600 hp range or so but after that you'll need dual Eddy carbs or switch to a big Holley.
