Gearing ?

Without actually driving to a track and testing things, this whole deal is just gonna cause a lot of confusion. I think some of these guys think you're gonna run 1/8 mile but your original post refers to quarter mile.
All you need to do is play around with an RPM calculator like this one, and find what combo gives you the highway RPM that you want......
Simple RPM Calculator | RANDYS Worldwide

Everyone is completely different on this subject every time, I personally like to do 65MPH at about 2300-2400 RPM's.
Some guys, like Marcohotrod mentioned, can buzz down the highway at 3000 and not care, his combo with a 5.13 gear actually puts him at 4100 RPM's at 65mph if he has a 28" tall tire. I would be able to tolerate that for about 3 minutes lol, and I've had a couple 9 second cars.