Use or don't use vacuum advance on distributor???????????????????

Carb shouldn't matter but its a 750 willys carb. 74 dart stock gears stock everything else. I am asking about adjusting the screw in the vacuum can on the distributer to make it work on manifold vacuum. I know its not a carb issue I'm asking if I can adjust a factory distributer to work with manifold vacuum.
OK, we'll go with that. You are asking the wrong question.
You don't adjust the vacuum advance to work with manifold vacuum. You tune the engine to work with the vacuum advance that uses manifold vacuum.
Have a good evening.