Use or don't use vacuum advance on distributor???????????????????

Revhendo said
It's a pretty carb, but it is conpletely wrong for your engine. It's completely wrong for your intake.

I wanna race your tuner.

First off he isn't my tuner. He is a friend of mine helping me out and we are tuning it together. I have been told by multiple people that a 750 holley is plenty good. Wrong for my intake how? Elaborate for me please.