3.8 #1 misfire on my grand caravan

These years of vans have a wiring harness that droops towards the exhaust manifold in the back of the engine over time. They have been known to melt and cause problems. Something to check into. I tied mine up with a stupid zip tie. I'm at 200k, and my brother is over 250k. We both have 3.3's, but they are basically the same engines externally. He has only replaced the water pump, and mine.... nothing