how much compression is too much?

The 557 lift cam P4120665 has specs of 296/296/110 and [email protected]
The ICA is about 74*, in at 106
This cam wants a lot of compression.
With an Scr of 11.0, the Dcr comes in at 8.2/164psi
With an Scr of 11.5, the Dcr comes in at 8.5/173psi
With an Scr of 12.0, the Dcr comes in at 8.87/183psi
With an Scr of 12.5, the Dcr comes in at 9.22/192psi
I run my 367 at 10.9/8.9/180 with aluminum heads , and 34* of power-timing and it burns 87E10, has for over 100,000 miles. My timing is delayed to all in at 3400rpm.It idles on 14 to 18. This on .034ish Quench.Street
I have also run 11.3/8.6/176 with a 292/108 cam; also on 87E10.This on .028ish quench.Street
That said, there are some fellows on FABO that have stated they run 400plus CID-engines with aluminum heads, at Dcrs of up to 9.3/200psi, on pump gas. Street.
Dcr is a guideline for determining freedom from detonation,generally below 3500 or so and up to perhaps the torque peak.
I know nothing about running WOT for 10 seconds atta time well above those rpms. I can say with confidence tho, that my engine has never detonated, even running up to 7200rpm, and/or up to 120 mph, and always on 87E10.
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Jus FYI. Pick your poison.lol