Locking Nuts v. FLanged Nuts

My vote is for Nylocks with locktite. They will never let go.
as someone who deals with these on a daily basis, NEVER use locktite on Nylocks. We have ran into multiple instances on our platforms we work on where the locktite actually destroys the nylon insert resulting it the erosion of the nylon and thus, loosening of the nut. So we have re-engineered everything to use simply nuts with Red or Blue Locktite depending on the the location of the nut.