Help Me Diagnose My Miss

Are you running a vacuum advance? And how is it plumbed? I have seen the Vcan pull the plate around and cause the spark to jump to the wrong tower. This happened to me. The cure for me was to re-index the reluctor and the rotor. You may wish to try running it with the can disconnected. You may have to rotate the distributor with the engine running,until it begins to run properly.
Or it could just be cracked insulators on a couple of plugs, due to detonation...........