Oh sure, I mean, you could modify a set of 5x100mm wheels and come up with a solution to make sure they were centered and not side loading the studs. It’s not a big difference and it wouldn’t take much, but you’d still have to do something to make sure everything was centered and no side loading was occurring.
But that’s not usually what people are talking about. They just want to bolt on a set of 5x100mm wheels because there’s actually decent wheel selection in that size, not because they’re looking to modify a set of wheels.
I dunno. You’re already running around on 50+ year old wheel studs that are only 7/16”. Personally, if I was going to spend much energy or money on it I would be upgrading to 5x4.5” and later brakes anyway.
