10.2 : 1 compression 360 at sea level. Options?

THAT is what the OP needs to be concerned about. (Possibly one reason that Holley and other aftermarket carbs seem to come out of the box a tad on the rich side.)

As long as his O2 sensor and AFR readout are accurate, and the OP isn't brain dead (lol), that should become apparent pretty quickly.

I find it interesting how other factors in your local air are obviously affecting how it runs. If you took the super dry mountain air from CO and simply compressed it to sea-level pressures you'd need like 100+ octane fuel, but I'm guessing where the OP now lives the air actually has some humidity to it...?

I still want to make a water/meth injection system for my Duster at some point, my engine would be grateful for the occasional cool spray down the nose when hauling a$$ up I-70 over the Continental Divide.