Connecting rod "offset"?

I was reading where factory Mopar small block connecting rods are "offset" and that most aftermarket connecting rods are not "offset". I wonder what is meant by "offset" and why or why not it is done. Thank you.
I assume it is done on V engines as it is probably very hard to get the paired crank journal centers exactly under the centers of 2 opposite banks cylinders, simply due to the geometry of the crank versus the block and keeping the mains as wide as possible.