Connecting rod "offset"?

As I said...all V-8 rods I can think of off the top of my head are offset. They have to be.

Yes you can flip the piston on the rod if the pin is offset but IMO it's a waste of time. The HP you MAY gain is minimal.
There is no HP "gain" to reversing piston offset, but the actual effects are very noticeable.
By reversing the offset, you are leaning the rod into the direction of crankshaft rotation earlier in the cycle giving peak cylinder pressure a bit more leverage to work the reciprocating assembly.
The engine will feel snappier and hit the converter harder.
I have done this on all of my own engines (when possible) over the last 40 years and can tell you first hand the back to back difference is profound