So called "Computer Compatible" cams are ground to maintain a high intake vacuum at idle and minimize the raw fuel that goes out the exhaust during the valves overlapping event.
Would a different grind give you more performance? It depends on your combination. Will it work? Of course. It has no idea you are using a carb, so go right ahead.
Once manifold vacuum at idle is lowered beyond a certain point by larger grinds with increased duration and subsequent increased overlap, the stock JTEC computers (Mopar ECM's) can not self-adjust the fuel trim parameters enough with the stock tuning that's programmed into them.
You can reprogram the stock computers to run with a very low manifold vacuum, large duration & overlap cam grinds and even larger injectors. That is what I had to do with the cam in my '68 EFI'd 408 using the stock computer.
