Help please

I have a 1984 225 slant 6, I just put brand new plugs and wires and everything on it and recently it started acting real Goofy, when I'm driving it down the road I step on the accelerator pedal and I hear an awful wine like a vacuum leak or something but it's not a sucking air sound as more of a whistle but it lets up when I let off the accelerator and it won't do it when I'm just sitting still at an idle it seems like the motor has to be under a load,... I'm freaking out and I need help