Holley sniper vs. Edelbrock pro flo

I doubt it's "other systems" vs Ed. There (to my knowledge) are three basic strategies

1...Mass air flow used by Ford eg
2...Air density used by EG Dodge, Holley, Megasquirt, FI tech, I don't know who all else
3...Or "Alpha N" which can be SELECTED by many systems. This primarily uses temp sensors like 1, 2, but instead of MAF or air density, it simply uses RPM and throttle position. THIS IS WHAT is used on stuff like "stack injection" (Hilborn style) or in some cases of "really big cams" with poor vacuum signal.

Frankly, it sounds like you might be "out of" the lower end Sniper/ FI tech relm. You might want to thing about Holley that uses an HP computer. ALL Holley systems except Sniper and the larger Dominator use an HP computer. The Avenger/ Terminator both use the HP computer, and if you want to step up later to multiport, you can still use most of the system, INCLUDING the throttle body.......just add the multiport injectors and reprogram the system.