318 poly w/ carter AFB rough running especially idle and off-idle.

Sounds like the idle mixture screw may have a bur on the threads somewhere. As long as the needle end is good, it should seat properly. Does the engine stumble when each screw is seated with it running?

When I start to screw in the mixture screws the car begins to stumble and at a certain point the engine will die once they are turned past a certain point.