Thermostat neck from Billet Technologies

And then when you take it apart at some future date, the o-ring will be ruined (you'll never get the RTV off of it). The o-ring is the seal. It needs no sealant.

The sealant is non hardening and will not ruin the o ring.

How often do you actually need to take the tstat out? I didnt pull mine in 5 years until i replaced the murray water pump with a milodon high flow and matched a high flow tstat to it