does locktite go bad?

What are you cleaning the bolts and bolt holes with? I know Loctite doesn't like oil.
Are the bolt holes too worn (good bolt or tap feels loose in the threads)?
"Loctite Threadlocker Blue 242 is designed for the locking and sealing of threaded fasteners which require normal disassembly with standard hand tools. The product cures when confined in the absence of air between close fitting metal surfaces."
"Loctite Threadlocker Red 271 is designed for the permanent locking and sealing of threaded fasteners. The product cures when confined in the absence of air between close fitting metal surfaces. It protects threads from rust and corrosion and prevents loosening from shock and vibration."
I think the hydraulic red Loctite can be hard on the aluminum threads for removal unless heated enough.