I am almost on board with this. However, a domed piston isn’t a bad thing if you have the open chamber to go with it. Something like the old TRW slugs and a open chambered OE head or W2’s. This is actually a good combo and would rather run this o sr a flat top and closed chamber but come today, there are no big open chambered heads available.
Now I can not absolutely prove they flow better or perform better because one can argue the piston is heavier and will slow down the entire rotating mass and/or not allow it to speed up (rpm) quickly vs a lighter flat top.
I get you can re work the closed chamber to a larger easier flowing chamber BUT there is only so much material you can remove. Sorry, I can’t say exactly how much can or can not be removed. It’s to general and a loaded question.
Currently, I run the flat top slugs and closed chambered heads. It works great by me. It’s what we got these days.