Jets and Power Valves 750 Holley 4150

run a PV a tad under your cruise vacuum regardless of idle vacuum
Mostly that would be on engines that are inefficient at part throttle.
agree... but he is asking about his initial setup. So the 1/2 idle vacuum is a easy starting point.
Seems reasonable.
The situation where it gets people in trouble is engines with very poor idle characteristics. An engine that idles with 5 "Hg, very well might need a PV that opens at 6 or 8"Hg or there will be a flat spot in part throttle acceleration.