Thermostats - high flow vs standard flow - now I am confused

So what are safe temps 180 to 200 run temp?
That would depend on the engine and the application, but yeah 180 to 200 should be safe for a streeter.
Generally; I've heard it said that the colder below 180 you run it the faster and the more it will wear. Yet on the dyno they often make best power at cooler temps.
Generally; I've heard it said that engines make better fuel mileage at higher temps, and that might be substantiated by the fact that most modern systems do run much hotter than in the old days.
I've run 207 since 2004. Makes good power, great fuel economy, and the engine has over 100,000 on it and still runs like a scalded dog. Your results may vary.....