Comprehensive Test Regular vs Premium

Winter fuel is allowed higher RVP than summer fuel. Makes for easier starting in cold weather and uses cheaper components. Get days with 80*F+ plus air temps and winter fuel and the lighter parts of that fuel are vaporizing. Drivability will go down. Vapor lock issue become more likely. Hot days and winter fuel are just bad news for us. May 1 is the mandatory date for refiners to supply Summer fuel. BUT, retailers have until June 1 to be fully switched over. Some states do not give E10 fuels extra allowance for higher RVP even in the areas which must sell reformulated fuel.
Date of switch to summer-grade gasoline approaches - Today in Energy - U.S. Energy Information Administration (EIA)
Gasoline-characteristics-street-pump-then-and-now

Fuel composition also varies with region. There's dozens of differerent requirements throughout the US and Canada, and so different formulations. Some of the requierments come from the EPA, some from the engine and vehicle manufactuers, etc. The mandated ethanol is just one of those requirements. Some states even have drivability requiments (good for us).
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For a good overview of gasoline read this:
http://www.chevronwithtechron.ca/products/documents/69083_MotorGas_Tech_Review.pdf
Topics include:
Gasoline and Driving Performance
"do." and Air Quality
Refining and Testing
Oxygenated fuels
Engine Deposits
Handling Safety
They also have a booklet on Av gas -but I don't have the link handy.

If you see references to Tier II EEE gasoline, that was a fuel created for the purpose of having a testing standard. Although siimilar, its not the same as what is sold for public use. For example in this study by Durbin et al