400 stroker

This is not a big deal.

You're going to mill the block anyway, right? So mill the block to 9.957" zero deck (-.023") instead of 9.980", mill the heads for 75 cc (What's that, about .018"?), use an .039" gasket and settle for 10.37:1 compression? I don't think you"ll be able to tell 10.5:1 to 10.37 compression difference. Oh, and you'll most likely have to mill the intake manifold and/or head intake surface a total .050".
Just wondering what guys usually do after they mill the intake surface of the head, to get the valley pan gasket to seal at the corners? Because there is now a .050" gap there at the corner where the pan meets the head. A small dab of silicone? The rails on the block can be milled too, I suppose, to make the block and head meet evenly.