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It would be doable in a short cycle engine as long as there were no head bolt or reinforcement bosses protruding downward from the deck that would cause the water jackets to get blocked. A flow cooler pump and aluminum heads would help, but not as much as an external oil cooler. The most important thing to do is to talk to your piston and ring tech support. The piston to wall clearance and the ring end gap clearance both need to be opened up to at least air cool settings, and a little extra doesn't hurt. How much wear do the cylinders have as far as oval and taper? .060 over pistons with file fit rings may still work. With a BCR girdle and caps, aluminum rods, and red line 50 weight oil, I wouldn't be afraid of running it on ethanol with 15:1 SCR and B1 heads, but numbers 5 and 6 would be the go-no go gauge according to if they needed sleeved. Anything is possible, but if it costs almost as much as an aftermarket block...