My 66 Valiant wagon......

Also have a new intake for the 225!

Now, my question is, what should I run for a Holley 4 barrel on this? I'm thinking somewhere in the 500CFM range?

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I believe the customary carb is the Holley 390CFM. I will say though that back in the 80’s when I didn’t know a thing, I was using an Edelbrock 600CFM on a Clifford intake and headers in a 72 stock motor in my daily driver 65 Dart.