Ultimate home defence pistol?

S&W 500 Magnum. If you miss the intruder will be deaf....and no doubt terrified. Seriously...weapon does not matter, the operator does. If you are not a good shot and capable of pointing a weapon at another human....and pulling the trigger... the "best" firearm is not all that important. I have 3 weapons loaded, in the safe. One is my carry gun, a Kahr PM40, A Kimber 1911...my wifes Raptor with a st of Crimson laser grips and the trusted Mossberg 12 Gauge. Years ago I was home alone. Was 1 a.m. and the dogs were freaking out. Looked out the front door to see a car at the gate, no headlights. Pointed the laser at the windshield, car hauled ***. Before anyone says...oh, maybe they were lost etc...I live at the bottom of a private community. Signs on both ways in. Out of the 4 houses that are occupied on my street I am the only one fenced in, with locked gates. Why would a person in need come to a house with locked gates and a fence, with beware of dogs and no trespassing signs, when not 300 feet a way there is an open driveway...and no signs warning of dogs?