massive reconfiguration time again.

I'm talking 65-70 on the freeway for 45 minutes steady...

I wind will be shifting directions continuously as you are driving down the road. The road swings to the left and the road swings to the right the airflow over your carburetors will be shifting from left to right.
The engine itself will be only drawing air through the carburetors that it wants. If you have 2000 CFM carburetors on top of that tunnel ram it will not matter if the engine demand is only 150 CFM.
In other words you're blocking of one side of your air cleaner is not going to do you any good.