Seam sealer on underside?

Well, I guess my crap's gonna rust all to hell. I am seam sealing every nook and cranny top and bottom where I replaced the floor pans. Ain't havin it. I'm sealin everything I can find. A coat of Rustoleum before and after.

I'm just going through this process now too. Floor plans are in and I was thinking to use 3M's seam sealer both inside and underneath. Primer first, then seam sealer, then truck bed liner.

If you seal the seams completely, would there be concerns, or does condensation still allow water to be present under all of that?