Timing recommendations for 12.2:1 E85 408

Given altitude of 6,000 ft (Denver) and my specs of 408 Ohio Crankshaft forged internals, H-rods, JE pistons 12.2:1 compression, custom solid FT 248/255 106lsa, Air-Gap intake, Holley XP 950 running E85 with the new Trick Flow Power Port 190 heads, where would you put timing? We have it at 36, but think we can get more out of her, but don't want to detonate obviously. Any thoughts from experience? We have it fired and it sounds pretty nasty, just haven't made the maiden voyage yet due to tranny linkage. Thanks for your opinions as always FABO!
You can advance timing at altitude, typically around 1degree for every 1000ft. I've advanced the cam some too.