Need some help, opinions.

Sad story.
I don't know if this is the place for getting advice on such a complex manner. IN my self admitted limited knowledge of aging and health concerns, it appears that she may have some form of age related depression. People with health problems often slip into depression and feel like life is over for them. You really should speak with a health care professional or a social worker to resolve this. She may be able to improve herself with some help.