Need some help, opinions.

My personal advice, coming from someone that sees that you wouldn't have conflict about this if you didn't care, is to explore options about treating the root cause of the problem: Depression.

The beauty of this is, if she's truly unmotivated to get up or do anything, then she'll either find motivation when they come to help her, by getting up to leave (an improvement over her current state), or she'll be unmotivated enough to sit and live through it, which may help her. Remember, rock bottom is that one has nothing left to lose, and it doesn't sound like y'all are there yet, although it is clear that you are exasperated with the situation and rightfully so. There are still options, so we know you're not at the end of your rope although this may feel like it right now (it will not always feel this way).

If she is depressed, she may feel like a burden to you, and want you to leave and be happy without being able to say that. I take this as a sign that she still cares about you, deeply. Consider asking her if this is true. Depression is a bizarro-reverso world in someone's head, compared to outside where things make more sense. Remember, this is not your fault, and it's not her fault, either.

Don't leave if your conscience tells you that you have haven't done everything yet. But take some time, and do something for yourself before you decide where to go next. It doesn't sound like she needs round-the-clock care, and you can enjoy your life and find strength to work through this. Volunteer somewhere. Make a gift for someone. GET SOME EXERCISE. Or just go for a drive. Any of these things will help you feel better, and help clear your head. If you're physically able, walk a few miles (but don't give yourself a heart attack doing so).
Sounds like you might be a bit depressed, yourself. Talk to a therapist. Ask your therapist about what to do, and discuss a deadline for change in you, or Mo. Once that point is reached, and you've done what you can, then you can leave and be at peace about it.

I have a friend who's wife had a massive aneurysm, and it drastically changed her, and no long after his daughter and grand-daughter passed away. He's a very good person, is dealing with it in his own way, and if you're interested, I can pass along to him and see if he'd like to talk with you (I bet he would), but even if he doesn't, know that there's at least one other person going through the same thing. That means that there are some nearby to you, too. Support groups are highly recommended, low-cost, and surprisingly effective at helping you cope, even if nothing else changes. They might even have one for Mo. You and Mo are NOT alone. This happens to many people, and it is not insurmountable even if it feels like it is right this minute.

PM me if you need to talk.