High compression and turbo

I wouldn't do it on gasoline. And spend for a custom turbo cam. It will spool quicker, put less heat in the exhaust etc.

Make damn sure you kill all quench and soften up the combustion chambers.

Do it like a Drag Week engine and do it with two fuels systems. One for gasoline to drive around on and the other for methanol for twisting up the boost.

With that CR I'd shy away from much boost on even race gas. Unless you call VP or ERC or Torco and let them pick your gasoline.

VP Q16 is a good fuel but comes at a premium. But with that CR I’m not sure you got a choice. The 2 tank thing is a brilliant idea. But on even premium PG i would always be worried. I personally would get a custom grind turbo spec cam. They can get you more in the ballpark with your specs.