400 stroker suggestions

I like what your thinking. The compression ratio can be higher without issue unless pump gas octane is.
The cam is always a center of debate and contention in what you should use. Everyone has there own ideas and of course, the par for course is your a fool for not following there suggestions.

My only suggestion for you on cams is get the most lift you can get to take advantage of the heads flow abilities in the duration you want that has the quickest rise on the lobes. I’d prefer to see the cam on a 108 rather than a 110 or worse yet, 112.