318 driver - cam change or not?

With the technical analysis of a few members who have more than demonstrated a thorough knowledge of cam design, I would think we could find a group of contenders and come up with a few cases of-

"this one works for just a 4 bbl and duals build with highway gears"
"this one's better with the above and 3.23s"
"this one adds some high end but drops low end 5%"
"this one kills MPG...because"

or the likes.