Battery relocation- is it possible to just use "remote battery posts" in the engine bay?

I have relocated quite a few batteries to the trunk, works well and I am not at all worried about a rear end collision resulting in a fire as a result. Both my Viper and my 10 Challenger have rear mounted batteries from the factory.. For me it is not about weight transfer as much as it is space in the engine compartment; I like the cleanliness it creates. I also run a battery cut off switch on my batteries which allows me to cut off all of the main power to the car. I have used welding cable (#0) and the last one I used Accel lightening cable in my Cuda. In the last 2 projects I am going to do (my 70 RR and 68 Cuda) I will probably do the same.

As to grounds; yes I run a heavy cable to the frame by the battery, I also ground the engine and run multiple grounds under the dash. I would run the same grounds regardless of where the battery is located.