Why not a 413 ?

should you run 2.19/1.88 valves in a 4.19 bore of a 413?

Some larger valve sizes may require a clearance chamfer at the top of the bore, right where the valves gets close. I never had one, but I thought I remember seeing that somewhere. Maybe intake only.
If you get to 4.25" inch bore, things get less scary.

I built a 413 for a 300K, long ram motor several years ago.
I know I had to notch the bores, but I can't remember if they were 2.14 or 2.19 valves. Took longer to reclean the block than it did to add the notches.