Mopar R1 block

So a 440”-450” engine size isn’t a good idea? The stroke I was considering is 4.125-4.25
Maybe 4.00-4.100 has better geometry with those heads?

i wouldn't if it was me. If i had it to do all over would ideally run a big bore and a 3.79 stroke crank with a W5 head.
But 4 inch will work fine.