small block heads for a long distance cruiser

We can all dream right? How about 13s and 20 mpg?

But seriously, I've got X heads that I could rebuild, but I was wondering if the EQs or LAX from Indy were worth spending some money on rather than stock heads. I understand that I can use stock rocker shafts and rockers with those, yes? I'm leaning to iron for long term durability but could be convinced otherwise. But I'm looking for something that would give it more kick from 1500 to 5000 rpm while being simple and durable.
I'm at low 13's with my 360 and though I've never checked, I believe I'd be around 18 mpg with stock 360 heads. I have 2.94 gears. I can drive an hour to the drag way, run it through a couple times, and drive it home for about 5-6 gallons?? if I remember correctly.