Help blochy paint

How long did you give the filler time to cure? hours minutes or days?? Bet that is the man problem. Polyester "primer" is sorta like spraying body filer also. Not sure about your polyester sealer.
I use epoxy primer over filler after it has had plenty of time to sure/shrink.

I admit I should have said I spray epoxy primer over filer then high fill sanding urethane primer block seal, then topcoat!! Like said the filer absorbs. After said and done, if I am ready to topcoat coat, if you see or fell anything it will affect the outcome.