That temperature (or colder if you don’t need a heater) will be hard on the engine IF you don’t tune for it. That’s one of the reasons I can run as much compression on pump gas as I do. I keep the temp down, make sure the crossover is blocked (or better yet, use an intake manifold that doesn’t even have a crossover) and tune accordingly. If you saw the tune up I run in my carb, you’d probably think it’s screaming lean.
Like everything else, you have to account for what you do.