I disagreed but only cuz I can't agree and disagree to the same post. You can't line hone the mains without moving the crank centerline a little bit (which is kinda what I heard you saying) but I do agree with you that ONLY if it's done right, it won't change it enough to need a special timing chain set.
That said, I don't know how gear drives compensate for this, even in a production-tolerance situation, let alone after machining. I put the tensioner on the timing chain in my small blocks so I never worried much about any of it.
