Synthetic oil use on flat tappet cam after break in

First off. Happy new year!!!! As I sit here waiting for the end of 2020 I am pondering an oily thought. Theres been other discussions about oil with ZDDP and zinc additives for these older V8s. Kinda curious if after a remanned break in you switch to a true synthetic oil if that negates the cam lobe wear and can be safely used in place of oils with ZDDP zinc additives etc.