Synthetic oil use on flat tappet cam after break in

I saw the benefit of synthetic oil in the late 80s, I was having trouble keeping 4.88 pro gears in my Plymouth more than 125 passes. A buddy said to try synthetic gearlube and I started pulling the ring & pinion at 400 passes just because it seamed like I should. That year I gave up on my Valvoline racing oil ( I still have five 5 gallon buckets of it) and went synthetic in everything.
THERE MUST BE SOMETHING TO IT , My 1990 thunderbird SC said to change supercharger oil every 60,000 miles, My 1992 Tbird SC said no oil change needed for the supercharger as they used synthetic oil in it , drove it 500,000 miles in 5 years never had a problem . The engineers believed in it , good enough for me .