What goodies do I need to build a Fast slant 6

Hi All
I’m wanting to build a fast cranky slant 225 6cyl !! Something between a drag, race engine but able to drive on the road.
I want it to have a lumpy cam and whatever else is needed to make some big HP numbers I’d like to get 300rwhp + .
I’m not a mechanic and don’t know what works to get that type of HP so I’d really appreciate it if those who have built these before, and have got these types of results!, if they could Please elaborate on what they did to there engines in detail so I can build something similar.
I have friends that are mechanics so hoping I can get the block, head and other engine bits and pieces and give it to them to put it together for me.
I’d really appreciate any help and you time letting me know.
Thanks
I think by the time you get done with the slant 6 & take it down a drag strip 1 day, you'll be wanting to go faster. Better to start with something that's easy to get 300 hp at the wheels, maybe 383 4bbl, they're alot cheaper than building a slant for power, what car are you building?