Heads, how much gain?

Are you talking ignition timing or cam timing?
Actually both. But starting with cam. I have always, and seen as well, cam degreeing at the centerline mark. (I'm very sure there are reasons to use the advanced/retard marks. Or why have them?) I just never had. My question? What can one expect by advancing? With relation to lets say ignition timing. And/or carb settings? ( I'm guessing you are going to say none. That advancing cam setting is only to move RPM power band earlier?) But I suspect it will affect ignition timing as well?