Timing marks

So I replaced my timing chain, spark plugs, installed 4 barrell carb and Edelbrock Performer on my 273. Takes a bit for it to start like the timing is off. When the engine is idling, I can't see the timing mark on the crank anywhere near the timing pointer. I removed the #1 plug and rotated the crank until TDC and the rotor points between #1 & 3. More toward #3. It's got spark and fuel. Just runs like **** and backfires. I loosed the rotor and turned the distributor to see if it smooths out but it doesn't. It dies when I give it gas.
Should I rotate the crank until the timing mark is around 10 degrees to see where the rotor is?