Can a 400BBM w/cheap aluminum heads compete/dominate against the street LS?

My 451 is close to thous numbers. I believe a little less compression. (Block was not decked to build. Thus pistons are a tick in the hole.) I'm guessing around 12.5:1. Running to a 1050 E-85 metered Holley 4150 style carb. (E-85 to accommodate the higher compression.)

The jury is still out on my thoughts of E-85? Does go thru more fuel. And needs flushing more frequent. Smells a little funny? Lol. But in Minnesota? ALOT cheaper than race gas.
Do you use it out of the pump or can.