New door panel question

The perforated square is for door latch. To the right the oval impressions are on the top of door panel. Should be on the bottom
Question for you: I can get replacement door panels, but they are not pre-cut. I would have to cut out the perforations for the door handle & pad as well as the vinyl. Is there any issue with cutting the vinyl? Will it be a problem where the vinyl would crack later where it was cut? Those panels are expensive, and I don't want any problems.